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Which patients may benefit from an increased bicarbonate concentration?

  1. Those with high potassium levels

  2. Poorly compliant with regards to fluid intake

  3. Those on a low protein diet

  4. Patients experiencing frequent infections

The correct answer is: Poorly compliant with regards to fluid intake

Increased bicarbonate concentration can be particularly beneficial for individuals with metabolic acidosis, which often occurs in patients with chronic kidney disease (CKD) or other conditions that lead to the accumulation of acids in the body. These patients may have difficulty excreting acidic waste products, resulting in a decrease in blood pH. When considering the choices presented, patients who are poorly compliant with fluid intake often struggle to maintain their electrolyte balance and overall acid-base homeostasis. In such cases, an increased bicarbonate concentration can help neutralize excess acids in their system, effectively improving their metabolic state and reducing the risk of complications associated with acidosis. This administration of bicarbonate can also enhance patients' overall health by supporting their body's ability to maintain a balanced pH level. The focus here is on the systemic effects of bicarbonate in managing chronic conditions that result in imbalances, particularly when fluid regulation is not adequately maintained. The other choices do not directly relate to conditions where increased bicarbonate would provide the most benefit in managing acid-base disturbances, making the chosen answer particularly relevant in the context of dialysis and kidney-related health issues.